# 📝 Exercise 01#

The aim of this exercise is to highlight caveats to have in mind when using feature selection. You have to be extremely careful regarding the set of data on which you will compute the statistic that helps your feature selection algorithm to decide which feature to select.

On purpose, we will make you program the wrong way of doing feature selection to gain insights.

First, you will create a completely random dataset using NumPy. Using the function np.random.randn, generate a matrix data containing 100 samples and 100,000 features. Then, using the function np.random.randint, generate a vector target with 100 samples containing either 0 or 1.

This type of dimensionality is typical in bioinformatics when dealing with RNA-seq. However, we will use completely randomized features such that we don’t have a link between the data and the target. Thus, the generalization performance of any machine-learning model should not perform better than the chance-level.

import numpy as np



Now, create a logistic regression model and use cross-validation to check the score of such a model. It will allow use to confirm that our model cannot predict anything meaningful from random data.

# Write your code here.


Now, we will ask you to program the wrong pattern to select feature. Select the feature by using the entire dataset. We will choose ten features with the highest ANOVA F-score computed on the full dataset. Subsequently, subsample the dataset data by selecting the features’ subset. Finally, train and test a logistic regression model.

You should get some surprising results.

# Write your code here.


Now, we will make you program the right way to do the feature selection. First, split the dataset into a training and testing set. Then, fit the feature selector on the training set. Then, transform both the training and testing sets before you train and test the logistic regression.

# Write your code here.


However, the previous case is not perfect. For instance, if we were asking to perform cross-validation, the manual fit/transform of the datasets will make our life hard. Indeed, the solution here is to use a scikit-learn pipeline in which the feature selection will be a pre processing stage before to train the model.

Thus, start by creating a pipeline with the feature selector and the logistic regression. Then, use cross-validation to get an estimate of the uncertainty of your model generalization performance.

# Write your code here.